Infertility affects millions of couples who desperately want to conceive a child but have been unsuccessful. There are many potential causes of infertility in both men and women. Exciting research shows that a hormone called gonadotropin-releasing hormone (GnRH), also known as Gonadorelin, may help increase fertility when used properly.

Overview of Gonadotropin-Releasing Hormone

GnRH is made and secreted in the hypothalamus of the brain. It then travels to the nearby pituitary gland and binds to receptors, triggering the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH). These downstream hormones stimulate the production of estrogen, testosterone, and sperm and egg development for fertility.

As we age, declining GnRH levels lead to reduced gonadotropin and sex hormone production, which can impair fertility. By supplementing with synthetic Gonadorelin to restore youthful hormone levels, fertility may be enhanced.

Gonadorelin Studies on Female Fertility

Several studies have explored the use of Gonadorelin to improve fertility

outcomes in women:

Improved Ovulation & Pregnancy Rates

A study gave women with ovulation issues a nasal spray of Gonadorelin. 78% of women ovulated compared to 36% in the control group. Pregnancy rates were also significantly higher.

Regulation of Menstrual Cycle

In women with irregular, absent, or abnormal menstrual cycles, daily Gonadorelin administration normalized cycles to 27-32 days with proper hormonal fluctuations. Restored ovulation.

Useful in Polycystic Ovary Syndrome

In women with PCOS, Gonadorelin pulses reinstated ovulation, regular menses, and normalized testosterone levels that improve fertility.

By Haadi